The incidence of measles in China from 1991 to 2008 was reviewed, and the nucleotide sequences from 1507 measles viruses (MeV) isolated during 1993 to 2008 were phylogenetically analyzed.The results showed that measles epidemics peaked approximately every 3 to 5 years with the range of measles cases detected between 56,850 and 140,048 per year.The

Pulmonary fibrosis is a devastating lung disease without effective treatment options.Sphingosine-1-phosphate receptor 3 (S1pr3), a receptor for the lipid signaling molecule sphingosine-1-phosphate, has been shown to mediate the development of pulmonary fibrosis, although the underlying mechanism is not fully understood.Here, we found increased expr

Robust transcriptional responses are critical for defense against infection.However, unrestrained immune responses can cause negative impacts such as damaging inflammation and slowed development.Here, we find that a class of transcriptional regulators previously associated with regulation of development in Caenorhabditis elegans, is also involved i

Protection and conservation are not feasible without a deeper knowledge of the cultural heritage of the subject of intervention.A careful analysis of documentation, a detailed visual inspection of surfaces, and a systematic diagnosis of the inner properties are the basis for planning preventive strategies of restoration.Digital noninvasive techniqu